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Movie Director: Bobby Farrelly, Peter Farrelly

Frank Detomello catches a cold. The inside of his body is known as the “City of Frank” to its inhabitants, two of which - white blood cell cop Osmosis Jones, and cold tablet Drixorial - team up to fight the invading viruses intent on taking over the City.

Movie actors: Shannon Molly (), Murray Bill (), Stein Ben (), Silver Joel (), Rock Chris (Osmosis Jones), Fishburne Laurence (Thrax), Hyde Pierce David (Drix), Norwood Brandy (Leah), Shatner William (Mayor Phlegmming), Howard Ron (Tom Colonic), Kid Rock (Kidney Rock), Olson Kenny (Kidney Rock), Krause Jason (Kidney Rock), C. Joe (Kidney Rock), Eulinberg Stefanie (Kidney Rock), Bones Jimmie (Kidney Rock), Uncle Kracker (Kidney Rock), Adams Jonathan (Additional Character Voice), Alazraqui Carlos (Additional Character Voice),

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